diff --git a/goldens/public-api/platform-browser/errors.api.md b/goldens/public-api/platform-browser/errors.api.md
index ead51d7ea4f..36cc6d35190 100644
--- a/goldens/public-api/platform-browser/errors.api.md
+++ b/goldens/public-api/platform-browser/errors.api.md
@@ -13,6 +13,8 @@ export const enum RuntimeErrorCode {
     // (undocumented)
     HYDRATION_CONFLICTING_FEATURES = 5001,
     // (undocumented)
+    INVALID_EVENT_ATTRIBUTE = 5203,
+    // (undocumented)
     NO_PLUGIN_FOR_EVENT = 5101,
     // (undocumented)
     ROOT_NODE_NOT_FOUND = -5104,
diff --git a/packages/platform-browser/src/browser/meta.ts b/packages/platform-browser/src/browser/meta.ts
index e2bc1c7a81f..bc9229db0b6 100644
--- a/packages/platform-browser/src/browser/meta.ts
+++ b/packages/platform-browser/src/browser/meta.ts
@@ -7,11 +7,14 @@
  */
 
 import {DOCUMENT, ɵDomAdapter as DomAdapter, ɵgetDOM as getDOM} from '@angular/common';
-import {Inject, Injectable} from '@angular/core';
+import {Inject, Injectable, ɵRuntimeError as RuntimeError} from '@angular/core';
+
+import {RuntimeErrorCode} from '../errors';
 
 /**
  * Represents the attributes of an HTML `<meta>` element. The element itself is
- * represented by the internal `HTMLMetaElement`.
+ * represented by the internal `HTMLMetaElement`. Event handler attributes, which start with
+ * `on`, are not allowed.
  *
  * @see [HTML meta tag](https://developer.mozilla.org/docs/Web/HTML/Element/meta)
  * @see {@link Meta}
@@ -133,6 +136,7 @@ export class Meta {
    */
   updateTag(tag: MetaDefinition, selector?: string): HTMLMetaElement | null {
     if (!tag) return null;
+    this._validateMetaDefinition(tag);
     selector = selector || this._parseSelector(tag);
     const meta: HTMLMetaElement = this.getTag(selector)!;
     if (meta) {
@@ -164,6 +168,7 @@ export class Meta {
     meta: MetaDefinition,
     forceCreation: boolean = false,
   ): HTMLMetaElement {
+    this._validateMetaDefinition(meta);
     if (!forceCreation) {
       const selector: string = this._parseSelector(meta);
       // It's allowed to have multiple elements with the same name so it's not enough to
@@ -197,6 +202,19 @@ export class Meta {
     return `"${value.replace(/\\/g, '\\\\').replace(/"/g, '\\"')}"`;
   }
 
+  private _validateMetaDefinition(tag: MetaDefinition): void {
+    for (const prop of Object.keys(tag)) {
+      const attributeName = this._getMetaKeyMap(prop);
+      if (attributeName.toLowerCase().startsWith('on')) {
+        throw new RuntimeError(
+          RuntimeErrorCode.INVALID_EVENT_ATTRIBUTE,
+          (typeof ngDevMode === 'undefined' || ngDevMode) &&
+            `The Meta service does not allow setting event handler attribute '${attributeName}' for security reasons.`,
+        );
+      }
+    }
+  }
+
   private _containsAttributes(tag: MetaDefinition, elem: HTMLMetaElement): boolean {
     return Object.keys(tag).every(
       (key: string) => elem.getAttribute(this._getMetaKeyMap(key)) === tag[key],
@@ -204,7 +222,7 @@ export class Meta {
   }
 
   private _getMetaKeyMap(prop: string): string {
-    return META_KEYS_MAP[prop] || prop;
+    return Object.hasOwn(META_KEYS_MAP, prop) ? META_KEYS_MAP[prop] : prop;
   }
 }
 
diff --git a/packages/platform-browser/src/errors.ts b/packages/platform-browser/src/errors.ts
index 432b6382594..5c964975f22 100644
--- a/packages/platform-browser/src/errors.ts
+++ b/packages/platform-browser/src/errors.ts
@@ -26,6 +26,7 @@ export const enum RuntimeErrorCode {
   SANITIZATION_UNSAFE_SCRIPT = 5200,
   SANITIZATION_UNSAFE_RESOURCE_URL = 5201,
   SANITIZATION_UNEXPECTED_CTX = 5202,
+  INVALID_EVENT_ATTRIBUTE = 5203,
 
   // Animations related errors (5300-5400 range)
   ANIMATION_RENDERER_ASYNC_LOADING_FAILURE = 5300,
diff --git a/packages/platform-browser/test/browser/meta_spec.ts b/packages/platform-browser/test/browser/meta_spec.ts
index 377b5930005..d0e048056f0 100644
--- a/packages/platform-browser/test/browser/meta_spec.ts
+++ b/packages/platform-browser/test/browser/meta_spec.ts
@@ -89,6 +89,26 @@ describe('Meta service', () => {
     expect(actual!.getAttribute('content')).toEqual('4321');
   });
 
+  it('should reject event handler attributes targeting a body meta tag', () => {
+    doc.body.appendChild(defaultMeta);
+
+    const evil = 'alert(1)';
+
+    expect(metaService.getTag('property="fb:app_id"')).toBe(defaultMeta);
+    expect(() =>
+      metaService.updateTag({
+        property: 'fb:app_id',
+        style: 'content-visibility:auto',
+        oncontentvisibilityautostatechange: evil,
+      }),
+    ).toThrowError(
+      /NG05203: The Meta service does not allow setting event handler attribute 'oncontentvisibilityautostatechange'/,
+    );
+
+    expect(defaultMeta.getAttribute('style')).toBeNull();
+    expect(defaultMeta.getAttribute('oncontentvisibilityautostatechange')).toBeNull();
+  });
+
   it('should not allow a custom selector to match off target elements like the body tag', () => {
     // This payload attempts to break out of the `meta[name="..."]` constraint entirely
     // and inject a comma to target arbitrary DOM elements like the `body` tag via the
@@ -143,6 +163,42 @@ describe('Meta service', () => {
     metaService.removeTagElement(actual);
   });
 
+  it('should reject event handler attributes without adding a tag', () => {
+    const selector = 'name="og:title"';
+    const evil = 'alert(1)';
+
+    expect(() =>
+      metaService.addTag({
+        name: 'og:title',
+        style: 'content-visibility:auto',
+        oncontentvisibilityautostatechange: evil,
+      }),
+    ).toThrowError(
+      /NG05203: The Meta service does not allow setting event handler attribute 'oncontentvisibilityautostatechange'/,
+    );
+
+    expect(metaService.getTag(selector)).toBeNull();
+  });
+
+  it('should reject event handler attributes in addTags without adding tags', () => {
+    const selector = 'name="og:title"';
+    const evil = 'alert(1)';
+
+    expect(() =>
+      metaService.addTags([
+        {
+          name: 'og:title',
+          style: 'content-visibility:auto',
+          oncontentvisibilityautostatechange: evil,
+        },
+      ]),
+    ).toThrowError(
+      /NG05203: The Meta service does not allow setting event handler attribute 'oncontentvisibilityautostatechange'/,
+    );
+
+    expect(metaService.getTag(selector)).toBeNull();
+  });
+
   it('should add httpEquiv meta tag as http-equiv', () => {
     metaService.addTag({httpEquiv: 'refresh', content: '3;url=http://test'});
 
@@ -155,6 +211,22 @@ describe('Meta service', () => {
     metaService.removeTagElement(actual);
   });
 
+  it('should add attributes whose names match Object prototype keys', () => {
+    const meta = metaService.addTag({
+      name: 'prototype-keys',
+      constructor: 'constructor',
+      toString: 'toString',
+      ['__proto__']: '__proto__',
+    })!;
+
+    expect(meta.getAttribute('constructor')).toEqual('constructor');
+    expect(meta.getAttribute('toString')).toEqual('toString');
+    expect(meta.getAttribute('__proto__')).toEqual('__proto__');
+
+    // clean up
+    metaService.removeTagElement(meta);
+  });
+
   it('should escape selector values when deriving the match selector', () => {
     // This payload attempts to prematurely close the attribute selector
     // and match another attribute.