diff --git a/packages/compiler-cli/src/ngtsc/typecheck/src/expression.ts b/packages/compiler-cli/src/ngtsc/typecheck/src/expression.ts
index c1b199c28db..4cf410fbf4a 100644
--- a/packages/compiler-cli/src/ngtsc/typecheck/src/expression.ts
+++ b/packages/compiler-cli/src/ngtsc/typecheck/src/expression.ts
@@ -178,12 +178,18 @@ class TcbExprTranslator implements AstVisitor {
 
     let literal = `{ ${properties.join(', ')} }`;
 
-    // If strictLiteralTypes is disabled, array literals are cast to `any`.
     if (!this.config.strictLiteralTypes) {
-      literal = `(${literal} as any)`;
+      // If strictLiteralTypes is disabled, array literals are cast to `any`.
+      literal = `${literal} as any`;
     }
 
-    return new TcbExpr(literal).addParseSpanInfo(ast.sourceSpan);
+    const expression = new TcbExpr(literal).addParseSpanInfo(ast.sourceSpan);
+
+    // Always parenthesize the literal, because for DOM bindings we may put it
+    // directly in the function body at which point TS might parse it as a block.
+    expression.wrapForTypeChecker();
+
+    return expression;
   }
 
   visitLiteralPrimitive(ast: LiteralPrimitive): TcbExpr {
diff --git a/packages/compiler-cli/src/ngtsc/typecheck/test/span_comments_spec.ts b/packages/compiler-cli/src/ngtsc/typecheck/test/span_comments_spec.ts
index 30cc82f0ddc..e211640e554 100644
--- a/packages/compiler-cli/src/ngtsc/typecheck/test/span_comments_spec.ts
+++ b/packages/compiler-cli/src/ngtsc/typecheck/test/span_comments_spec.ts
@@ -40,7 +40,7 @@ describe('type check blocks diagnostics', () => {
       // statement, which would wrap it into parenthesis that clutter the expected output.
       const TEMPLATE = '{{ m({foo: a, bar: b}) }}';
       expect(tcbWithSpans(TEMPLATE)).toContain(
-        '(this).m /*3,4*/({ "foo" /*6,9*/: ((this).a /*11,12*/) /*11,12*/, "bar" /*14,17*/: ((this).b /*19,20*/) /*19,20*/ } /*5,21*/) /*3,22*/',
+        '((this).m /*3,4*/(({ "foo" /*6,9*/: ((this).a /*11,12*/) /*11,12*/, "bar" /*14,17*/: ((this).b /*19,20*/) /*19,20*/ } /*5,21*/)) /*3,22*/)',
       );
     });
 
@@ -49,7 +49,7 @@ describe('type check blocks diagnostics', () => {
       // statement, which would wrap it into parenthesis that clutter the expected output.
       const TEMPLATE = '{{ m({a, b}) }}';
       expect(tcbWithSpans(TEMPLATE)).toContain(
-        '((this).m /*3,4*/({ "a" /*6,7*/: ((this).a /*6,7*/) /*6,7*/, "b" /*9,10*/: ((this).b /*9,10*/) /*9,10*/ } /*5,11*/) /*3,12*/)',
+        '((this).m /*3,4*/(({ "a" /*6,7*/: ((this).a /*6,7*/) /*6,7*/, "b" /*9,10*/: ((this).b /*9,10*/) /*9,10*/ } /*5,11*/)) /*3,12*/)',
       );
     });
 
diff --git a/packages/compiler-cli/src/ngtsc/typecheck/test/type_check_block_spec.ts b/packages/compiler-cli/src/ngtsc/typecheck/test/type_check_block_spec.ts
index a51d93b7be1..5f72d78490b 100644
--- a/packages/compiler-cli/src/ngtsc/typecheck/test/type_check_block_spec.ts
+++ b/packages/compiler-cli/src/ngtsc/typecheck/test/type_check_block_spec.ts
@@ -31,7 +31,7 @@ describe('type check blocks', () => {
 
   it('should generate literal map expressions', () => {
     const TEMPLATE = '{{ method({foo: a, bar: b}) }}';
-    expect(tcb(TEMPLATE)).toContain('(this).method({ "foo": ((this).a), "bar": ((this).b) })');
+    expect(tcb(TEMPLATE)).toContain('(this).method(({ "foo": ((this).a), "bar": ((this).b) }))');
   });
 
   it('should generate literal array expressions', () => {
@@ -39,6 +39,11 @@ describe('type check blocks', () => {
     expect(tcb(TEMPLATE)).toContain('(this).method([((this).a), ((this).b)])');
   });
 
+  it('should parenthesize literal maps bound to DOM properties', () => {
+    const TEMPLATE = '<div [class]="{foo: true, bar: false}"></div>';
+    expect(tcb(TEMPLATE)).toContain('if (true) { ({ "foo": true, "bar": false }); }');
+  });
+
   it('should handle non-null assertions', () => {
     const TEMPLATE = `{{a!}}`;
     expect(tcb(TEMPLATE)).toContain('((((this).a))!)');
@@ -112,8 +117,8 @@ describe('type check blocks', () => {
   });
 
   it('should handle "in" expressions', () => {
-    expect(tcb(`{{'bar' in {bar: 'bar'} }}`)).toContain(`(("bar") in ({ "bar": "bar" }))`);
-    expect(tcb(`{{!('bar' in {bar: 'bar'}) }}`)).toContain(`!((("bar") in ({ "bar": "bar" })))`);
+    expect(tcb(`{{'bar' in {bar: 'bar'} }}`)).toContain(`(("bar") in (({ "bar": "bar" })))`);
+    expect(tcb(`{{!('bar' in {bar: 'bar'}) }}`)).toContain(`!((("bar") in (({ "bar": "bar" }))))`);
   });
 
   it('should handle "instanceof" expressions', () => {
@@ -1878,7 +1883,7 @@ describe('type check blocks', () => {
       `;
 
       expect(tcb(TEMPLATE)).toContain(
-        'new IntersectionObserver(null!, { "rootMargin": "123px" }); "" + ((this).main()); "" + ((this).placeholder());',
+        'new IntersectionObserver(null!, ({ "rootMargin": "123px" })); "" + ((this).main()); "" + ((this).placeholder());',
       );
     });
   });